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Application
The application of platelet rich plasma has been documented in many fields, ranging from hard tissue regeneration to soft tissue management. Due to its ability to induce collagen synthesis by dermal fibroblasts, platelet rich plasma has been proposed as a promising treatment option in the field of skin care.
For a few years, it has been successfully used in numerous skin care applications, including alopecia, scar revision, acne scars, stretch marks, skin rejuvenation and dermal augmentation. For some indications, platelet rich plasma may be used in association with other treatment modalities such as laser, radiofrequency or fat grafting, to improve clinical outcomes.
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Advantages of Regen Kits
Platelet rich plasma shortens the different phases of the natural healing process, as it is prepared from autologous blood it eliminates the risk of immune reactions or transmission of infectious diseases. Platelet rich plasma prepared with Regen Kits acts not only as a course of multiple enhanced growth factors, which stimulates cell proliferation, but also as tridimensional (3D) bioactive scaffold, which enhances cell migration and new extracellular matrix deposition.
- Improvement of skin texture and tone
- Gradual increase in skin thickness2
- Can be used for sensitive areas
- May be combined with other treatment modalities such as laser, radiofrequency or fat grafting to stimulate biological effect. Platelet rich plasma should never be combined with other injectable treatments during the same session.
- Red blood cells are removed at 99.7%
- White blood cell levels are drastically reduced, with a preferential depletion (96.7%) of the pro-inflammatory granulocytes
- Regen Lab separator gel allows for the easy, rapid and consistent preparation
- Platelet recovery rate is above 80%
- Platelet concentration factor in Regen Kits is 1.6 fold over baseline value in blood (1.6X) Regen Kits are a fast, one-step, easy-to-use closed circuit system
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Frequently Asked Questions
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Features and Benefits
- Fully automated process
- Simple and easy procedure
- Process in closed circuit: Blood in, short centrifugation, platelet rich plasma out
- Blood component separation at the cellular level
- High recovery (>80%) of fully functional platelets
- Low level of undesired cellular contaminants
- Anticoagulant comes already in the device
egenlab uses Sodium Citrate as their anticoagulant which is a fully reversible anticoagulant. Sodium citrate is anticoagulant and has a neutral pH (pH=7) and has no ancillary effect on the patient. The benefit for using sodium citrate is that the pH level of the plasma does not change like it would with ACD-A anticoagulant. ACD-A is an anticoagulant often used for other plasma preparation, ACD-A is highly acidic (pH=4.5-5), contains hyperomolar dextrose and triggers more discomfort on application than sodium citrate. The anticoagulant comes already in the tube making it a closed loop circuit.
- Quality and Efficiency
- Fully automated process, simple and easy procedure
- Blood component separation at the cellular level
- High recovery (80%) of fully functional platelets
- Extremely low level of undesired cellular contaminants
- Regen Kits are Medical Devices for therapeutic use, not blood collection tubes.
- Platelets and plasma remain over the separator gel in the upper part of the device with a few mononuclear white blood cells. The rest of the buffy coast is trapped below the separator gel with the red blood cells in the lower part of the device.
Typically, first results are visible 2 weeks after treatment and full results around 4 months after, as platelets stimulate the release of growth factors which assist in collagen regeneration. Increasing the collagen in the patient’s skin means over time the skin will appear younger and fresher looking. Results will vary from one individual to the other.
Regen recommends the use of ATS serum to jellify plasma for face injections, the combination of platelet rich plasma with ATS serum should be injected as soon as prepared, as it will rapidly form a clot. Regen Lab advises to use a 1ml syringe filled with 0.9ml of plasma and 0.1ml of ATS serum. The combination is injected using the same technique as a filler though it is not to be described as a filler. It needs to be injected very quickly otherwise it will solidify in the syringe. A platelet gel will form at the site of injection. This will ensure a more localised action, as the product will not diffuse, to treat specific zones such as deep wrinkles or dark circles. For the periorbital area, perform injections of small amounts of the mix around the orbit, avoiding the internal eye’s angle. Immediately after the injections, massage the orbital area from up to down to spread the thrombin gel.
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Jan Marini Skin Research
Jan Marini Skin Research (JMSR) – a San Jose, a USA-based company founded in 1994. We have partnered with JMSR since 2001.
JMSR is a recognised leader and innovator in skincare formulations and is committed to continually expanding and improving the professional skincare market.
JMSR’s primary focus is to provide innovative skin formulation technologies that deliver proven and measurable results.